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SCAN (2009) 4, 313–327 Medial cortex activity, self-reflection anddepression Marcia K. Johnson, Susan Nolen-Hoeksema, Karen J. Mitchell, and Yael LevinDepartment of Psychology, Yale University, PO Box 208205, New Haven, CT 06520-8205, USA Using functional magnetic resonance imaging, we investigated neural activity associated with self-reflection in depressed[current major depressive episode (MDE)] and healthy control participants, focusing on medial cortex areas previously shownto be associated with self-reflection. Both the MDE and healthy control groups showed greater activity in anterior medial cortex(medial frontal gyrus, anterior cingulate gyrus) when cued to think about hopes and aspirations compared with duties andobligations, and greater activity in posterior medial cortex (precuneus, posterior cingulate) when cued to think about dutiesand obligations (Experiment 1). However, the MDE group showed less activity than controls in the same area of medial frontalcortex when self-referential cues were more ambiguous with respect to valence (Experiment 2), and less deactivation in a non-self-referential condition in both experiments. Furthermore, individual differences in rumination were positively correlated withactivity in both anterior and posterior medial cortex during non-self-referential conditions. These results provide convergingevidence for a dissociation of anterior and posterior medial cortex depending on the focus of self-relevant thought. They alsoprovide neural evidence consistent with behavioral findings that depression is associated with disruption of positively valencedthoughts in response to ambiguous cues, and difficulty disengaging from self-reflection when it is appropriate to do so.

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The Sec6兾8 complex in mammalian cells: Characterization of mammalian Sec3,subunit interactions, and expressionof subunits in polarized cellsHugo T. Matern*, Charles Yeaman†, W. James Nelson†, and Richard H. Scheller*‡ *Genentech, Inc., Department of Richard Scheller, 1 DNA Way, South San Francisco, CA 94080-4990; and †Department of Molecular and Cellular Physiology,Stanford University Medical School, Stanford, CA 94305

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Noninvasive Ventilation in Acute CardiogenicPulmonary Edema: Systematic Review and Online article and related content Josep Masip; Marta Roque; Bernat Sánchez; et al. current as of August 27, 2008. JAMA. 2005;294(24):3124-3130 (doi:10.1001/jama.294.24.3124) Topic collections Quality of Care; Evidence-Based Medicine; Review; Critical Care/ Intensive CareMedicine; Adult Critical Care

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Information Critical Care Management of the Adult Patient In Ireland with Ebola Virus Disease 2014 / 2015 Report of : Critical Care Advisory Group on Ebola Virus Disease Intensive Care Society of Ireland Interim Guidelines Update 4th January 2015 (to be updated with evolving international guidelines)

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Wiri Wai Care Wonders! Students from Wiri Central School proudly sign W after completing work on the Puhinui stream. Learning goes beyond the classroom Drury School drain painting Wai Care Fieldtrip to Hunua Brendon with a longfin eel found during fish monitoring Drury School's Wai Care club recently painted up a Papakura Normal School's middle and senior

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Validation of a brief questionnaire measuring positive mindset in patients with uveitis

Psychology, Community & Health 2182-438X Validation of a Brief Questionnaire Measuring Positive Mindset in PatientsWith Uveitis John A. Barry, Annie Folkard, William Ayliffe Please note that in the table in the Appendix, the fifth option for item 1 should be "Very happy", not "Very unhappy". [The author requested to add this note post-publication on 2014-04-08.]

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Recommendations for improved sustainable priority Neglected Species NUS in Vietnam Nguyen Lam, Nguyen The Phuong and Pham Thi Dung Funded by the European Commission's sixth framework programme: "Integrating and Strengthening the European Research Area, Specific Measures in Support of International Cooperation (INCO)". fp6-2002-inco-dev/ssa-1 – 026293

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